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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1997-2-28
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pubmed:abstractText |
Results of dry eye tests and ocular symptoms were compared and correlated in patients with primary Sjögren's syndrome (1 degree SS), in patients with connective tissue disease differing from 1 degree SS, and in normal controls. Patients with 1 degree SS had many and pronounced ocular complaints, however, non-diagnostic for the disease. Break-up time and Schirmer-1 test results below 10 mm/5 min both had high sensitivity but low specificity, whereas the reverse was true for Rose-Bengal score and Schirmer-1 test below 5 mm/5 min. Presence of snake-like chromatin in conjunctival imprints and the lactotest on tear fluid did not qualify as alternative tests since they had very low specificity and were less sensitive than the Schirmer-1 test and break-up time. Cornea sensitivity was not found to be an appropriate test at all. In 21% of eyes the presence of keratoconjunctivitis sicca changed from one consultation to the next in patients with 1 degree SS. Examination for keratoconjunctivitis sicca should therefore be repeated in test negative cases where symptoms indicate 1 degree SS.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1395-3907
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
436-41
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8950390-Adult,
pubmed-meshheading:8950390-Aged,
pubmed-meshheading:8950390-Aged, 80 and over,
pubmed-meshheading:8950390-Diagnosis, Differential,
pubmed-meshheading:8950390-Diagnostic Tests, Routine,
pubmed-meshheading:8950390-Female,
pubmed-meshheading:8950390-Humans,
pubmed-meshheading:8950390-Keratoconjunctivitis Sicca,
pubmed-meshheading:8950390-Lactoferrin,
pubmed-meshheading:8950390-Male,
pubmed-meshheading:8950390-Middle Aged,
pubmed-meshheading:8950390-Prevalence,
pubmed-meshheading:8950390-Questionnaires,
pubmed-meshheading:8950390-Sensitivity and Specificity,
pubmed-meshheading:8950390-Sjogren's Syndrome,
pubmed-meshheading:8950390-Tears
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pubmed:year |
1996
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pubmed:articleTitle |
Test and symptoms in keratoconjunctivitis sicca and their correlation.
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pubmed:affiliation |
Department of Ophthalmology, Rigshospitalet and Eye Pathology Institute, University of Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|