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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1997-1-7
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pubmed:databankReference |
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pubmed:abstractText |
A family of SRY-related genes has been termed SOX. We have isolated and sequenced a cDNA encoding a novel Sox protein from Xenopus laevis ovary. This cDNA contains an open reading frame (ORF) coding for 362 amino acids, which encompasses an HMG box and exhibits a strong (90%) identity to that of mouse Sox7; the cDNA was named xSox7 in this study. Northern analysis revealed that the xSox7 mRNA was 2.0 kb in length. Various adult frog tissues were tested by reverse transcription/polymerase chain reaction for xSox7 mRNA, and the results showed that xSox7 is expressed in a wide range of tissues. Furthermore, electrophoretic mobility shif assay indicated that recombinant xSox7 is capable of binding to AACAAT sequence.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-3002
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
1309
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
73-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8950180-Animals,
pubmed-meshheading:8950180-Cloning, Molecular,
pubmed-meshheading:8950180-DNA, Complementary,
pubmed-meshheading:8950180-DNA-Binding Proteins,
pubmed-meshheading:8950180-Female,
pubmed-meshheading:8950180-Gene Expression Regulation, Developmental,
pubmed-meshheading:8950180-High Mobility Group Proteins,
pubmed-meshheading:8950180-Organ Specificity,
pubmed-meshheading:8950180-Ovary,
pubmed-meshheading:8950180-RNA, Messenger,
pubmed-meshheading:8950180-Recombinant Fusion Proteins,
pubmed-meshheading:8950180-SOXF Transcription Factors,
pubmed-meshheading:8950180-Sequence Homology, Amino Acid,
pubmed-meshheading:8950180-Transcription Factors,
pubmed-meshheading:8950180-Xenopus Proteins,
pubmed-meshheading:8950180-Xenopus laevis
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pubmed:year |
1996
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pubmed:articleTitle |
Cloning and characterization of Xenopus laevis xSox7 cDNA.
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pubmed:affiliation |
Department of Anatomy, Keio University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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