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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1996-12-24
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pubmed:abstractText |
The combination of 5-fluorouracil (5FU) and radiation results in improved tumor control in a variety of gastrointestinal cancers. We propose the enhancement is related to radiation potentiating the antitumor effects of 5FU. To better understand the mechanism of the 5FU-radiation interaction, 19F nuclear magnetic resonance (NMR) spectroscopy experiments were performed to observed the tumor clearance and metabolism of 5FU.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0360-3016
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
641-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8948349-Animals,
pubmed-meshheading:8948349-Antimetabolites, Antineoplastic,
pubmed-meshheading:8948349-Female,
pubmed-meshheading:8948349-Fluorouracil,
pubmed-meshheading:8948349-Humans,
pubmed-meshheading:8948349-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8948349-Mice,
pubmed-meshheading:8948349-Mice, Nude,
pubmed-meshheading:8948349-Neoplasms,
pubmed-meshheading:8948349-Rats,
pubmed-meshheading:8948349-Sensitivity and Specificity,
pubmed-meshheading:8948349-Time Factors,
pubmed-meshheading:8948349-Tumor Cells, Cultured
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pubmed:year |
1996
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pubmed:articleTitle |
Tumor retention of 5-fluorouracil following irradiation observed using 19F nuclear magnetic resonance spectroscopy.
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pubmed:affiliation |
Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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