Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1997-3-5
|
pubmed:abstractText |
The present study evaluated the induction of micronuclear potency of indigenously developed bone wax saline extract. The experiment was designed with 2 batches, each consisting of 8 groups with 3 male Swiss albino mice each. In each batch, the first 3 groups received Chitra's bone wax saline extract and the second 3 groups received Johnson & Johnson bone wax saline extract at 12.5, 25.0 or 50.0 ml/kg body weight ip for 2 d. The remaining 2 groups were vehicle (saline) and positive (cyclophosphamide) controls. Animals were sacrificed 24 and 36 h after the second dosing and bone marrow smears were prepared and evaluated for micronuclei. The Chitra's and Johnson & Johnson's bone wax extracts failed to induce micronuclei in bone marrow erythrocytes of mice.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0145-6296
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
427-8
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8948073-Animals,
pubmed-meshheading:8948073-Biocompatible Materials,
pubmed-meshheading:8948073-Bone Marrow,
pubmed-meshheading:8948073-Bone Marrow Cells,
pubmed-meshheading:8948073-Cyclophosphamide,
pubmed-meshheading:8948073-Erythrocytes,
pubmed-meshheading:8948073-Male,
pubmed-meshheading:8948073-Mice,
pubmed-meshheading:8948073-Micronuclei, Chromosome-Defective,
pubmed-meshheading:8948073-Saline Solution, Hypertonic,
pubmed-meshheading:8948073-Waxes
|
pubmed:year |
1996
|
pubmed:articleTitle |
Effect of bone wax extract on the frequency of bone marrow erythrocyte micronuclei in mice.
|
pubmed:affiliation |
Toxicology Group, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojapura, Thiruvananthapuram, India.
|
pubmed:publicationType |
Journal Article
|