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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-1-6
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pubmed:databankReference | |
pubmed:abstractText |
The nucleotide sequence of hepatitis G virus (HGV) genome was determined by analysis of cDNA clones obtained by long reverse transcription-polymerase chain reaction (long RT PCR) and 5'- and 3'-rapid amplification of cDNA ends (RACE) from a Japanese patient (Iw) with non A-E hepatitis. The HGV-Iw genome, consisting of 9375 nucleotides, contains a long open reading frame encoding 2873 amino acid residues. Comparison of HGV-Iw with two American isolates of HGV and one African isolate of GB virus C (GBV-C) indicates that although the nucleotide sequences of these isolates were considerably divergent (86.2% to 93.3%), the deduced amino acid sequences shared an extremely high degree of identity (96.1% to 100%). It was also found that HGV-Iw was more closely related to the HGV isolates from USA than to the GBV-C isolate from Africa.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
228
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
785-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8941354-Cloning, Molecular,
pubmed-meshheading:8941354-DNA, Complementary,
pubmed-meshheading:8941354-Flaviviridae,
pubmed-meshheading:8941354-Genome, Viral,
pubmed-meshheading:8941354-Humans,
pubmed-meshheading:8941354-Japan,
pubmed-meshheading:8941354-Molecular Sequence Data,
pubmed-meshheading:8941354-Polymerase Chain Reaction,
pubmed-meshheading:8941354-Sequence Homology, Amino Acid,
pubmed-meshheading:8941354-Transcription, Genetic,
pubmed-meshheading:8941354-Viral Proteins
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pubmed:year |
1996
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pubmed:articleTitle |
Sequence of hepatitis G virus genome isolated from a Japanese patient with non-A-E-hepatitis: amplification and cloning by long reverse transcription-PCR.
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pubmed:affiliation |
Second Department of Internal Medicine, Yamagata University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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