8939149

Source:http://linkedlifedata.com/resource/pubmed/id/8939149

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0004096, umls-concept:C0034656, umls-concept:C0081408, umls-concept:C0205178, umls-concept:C0205191, umls-concept:C0206012, umls-concept:C1096776, umls-concept:C1257890, umls-concept:C1280500, umls-concept:C1289971, umls-concept:C2603343
pubmed:issue	5 Pt 1
pubmed:dateCreated	1997-1-13
pubmed:abstractText	Leukotrienes produced by the 5-lipoxygenase pathway of arachidonic acid metabolism may mediate bronchoconstriction and inflammatory changes important in the pathophysiology of asthma. Leukotriene inhibition may be effective in asthma management.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/1275002
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Agonists, http://linkedlifedata.com/resource/pubmed/chemical/Anti-Asthmatic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Histamine Antagonists, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyurea, http://linkedlifedata.com/resource/pubmed/chemical/Leukotrienes, http://linkedlifedata.com/resource/pubmed/chemical/Lipoxygenase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/zileuton
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	0091-6749
pubmed:author	pubmed-author:DubéL MLM, pubmed-author:LancasterJJ, pubmed-author:LiuM CMC
pubmed:issnType	Print
pubmed:volume	98
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	859-71
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:8939149-Adolescent, pubmed-meshheading:8939149-Adrenergic beta-Agonists, pubmed-meshheading:8939149-Adult, pubmed-meshheading:8939149-Anti-Asthmatic Agents, pubmed-meshheading:8939149-Asthma, pubmed-meshheading:8939149-Bronchoconstriction, pubmed-meshheading:8939149-Double-Blind Method, pubmed-meshheading:8939149-Drug Therapy, Combination, pubmed-meshheading:8939149-Eosinophils, pubmed-meshheading:8939149-Female, pubmed-meshheading:8939149-Forced Expiratory Volume, pubmed-meshheading:8939149-Histamine Antagonists, pubmed-meshheading:8939149-Humans, pubmed-meshheading:8939149-Hydroxyurea, pubmed-meshheading:8939149-Leukocyte Count, pubmed-meshheading:8939149-Leukotrienes, pubmed-meshheading:8939149-Lipoxygenase Inhibitors, pubmed-meshheading:8939149-Liver Function Tests, pubmed-meshheading:8939149-Male, pubmed-meshheading:8939149-Middle Aged, pubmed-meshheading:8939149-Time Factors, pubmed-meshheading:8939149-Treatment Outcome
pubmed:year	1996
pubmed:articleTitle	Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study Group.
pubmed:affiliation	Department of Medicine, Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224-6801, USA.
pubmed:publicationType	Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study