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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-12-24
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pubmed:abstractText |
Allele- and genotype frequencies for the polymerase chain reaction-based DNA genetic marker HLA-DQA1 were determined previously in a Swiss sample population (n = 200). In this study we subtyped the allele 4 in the same Swiss Caucasian population sample (distinguishing the 4.1 allele from the 4.2 and 4.3 alleles) using the AmpliType PM+ DQA1 PCR Amplification and Typing Kit. No deviations from Hardy-Weinberg equilibrium could be observed. The power of discrimination (Pd) of the HLA-DQA1 locus without subtyping the 4 allele for Swiss Caucasians was 0.931, when subtyping the 4 allele the value is 0.938. The frequency data can be used in forensic analyses to estimate the frequency of a HLA-DQA1 profile in the Swiss population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0379-0738
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-30
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8939010-Alleles,
pubmed-meshheading:8939010-Genetics, Population,
pubmed-meshheading:8939010-Genotype,
pubmed-meshheading:8939010-HLA-DQ Antigens,
pubmed-meshheading:8939010-HLA-DQ alpha-Chains,
pubmed-meshheading:8939010-Humans,
pubmed-meshheading:8939010-Polymerase Chain Reaction,
pubmed-meshheading:8939010-Switzerland
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pubmed:year |
1996
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pubmed:articleTitle |
HLA-DQA1 subtyping data in the Swiss population.
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pubmed:affiliation |
Institute of Legal Medicine, University of Bern, Switzerland.
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pubmed:publicationType |
Journal Article
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