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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1997-4-10
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pubmed:abstractText |
The effects of antifungal agents, with different mechanisms of action, on the morphogenetic transformation by synchronised yeast-phase Candida albicans cells in vitro and their respective anti-Candida activities are described. MIC data demonstrated that the azoles, amphotericin B and echinocandin were the most active agents against four C. albicans strains. Morphogenetic transformation experiments demonstrated that amphotericin B was significantly better at preventing the transformation, under a variety of test conditions, than the azoles and flucytosine: amphotericin B abolished the transformation at low concentrations while the azoles only prevented the morphogenetic transformation at much higher concentrations (> 100 x MIC).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0305-7453
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-87
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8937953-Antifungal Agents,
pubmed-meshheading:8937953-Candida albicans,
pubmed-meshheading:8937953-Cell Culture Techniques,
pubmed-meshheading:8937953-Cell Cycle,
pubmed-meshheading:8937953-Microbial Sensitivity Tests,
pubmed-meshheading:8937953-Morphogenesis,
pubmed-meshheading:8937953-Transformation, Genetic
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pubmed:year |
1996
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pubmed:articleTitle |
The effects of antifungal agents on the morphogenetic transformation by Candida albicans in vitro.
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pubmed:affiliation |
Lepetit Research Center, Marion Merrell Dow Research Institute, Varese, Italy.
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pubmed:publicationType |
Journal Article
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