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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1997-2-13
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pubmed:abstractText |
Carbon Dioxide Laser ablation therapy was originally offered to 25 women with Vaginal Intraepithelial Neoplasia (VAIN). The disease was primary in 12 and secondary after a previous hysterectomy in 13 cases. Treatment was accomplished under local anesthesia in 22 cases and was well-tolerated by all patients. The age of the patients ranged from 19 to 68 with a mean age of 44 years. All women were followed-up by cytology and colposcopy within a time period of 35 to 82 months (mean 49 months). Eight patients relapsed resulting in a failure rate of 32%. A second Laser CO2 treatment was offered to these patients with a final cure rate of 84% (21/25). The four cases in which the disease reappeared, after the 2nd treatment, were managed by upper colpectomy (3 cases) and follow-up (1 case). Laser CO2 ablation is an acceptable treatment modality for VAIN considering the promising cure rates and the preservation of the anatomic integrity of the vagina. Close colposcopic follow-up of these patients is necessary for early detection of disease relapses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0392-2936
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
389-92
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8933838-Adult,
pubmed-meshheading:8933838-Aged,
pubmed-meshheading:8933838-Ambulatory Surgical Procedures,
pubmed-meshheading:8933838-Carbon Dioxide,
pubmed-meshheading:8933838-Carcinoma in Situ,
pubmed-meshheading:8933838-Evaluation Studies as Topic,
pubmed-meshheading:8933838-Female,
pubmed-meshheading:8933838-Follow-Up Studies,
pubmed-meshheading:8933838-Humans,
pubmed-meshheading:8933838-Laser Therapy,
pubmed-meshheading:8933838-Middle Aged,
pubmed-meshheading:8933838-Postoperative Complications,
pubmed-meshheading:8933838-Vaginal Neoplasms
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pubmed:year |
1996
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pubmed:articleTitle |
Conservative management of vaginal intraepithelial neoplasia (VAIN) by laser CO2.
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pubmed:affiliation |
1st Department of Obstetrics and Gynecology, Athens University, Greece.
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pubmed:publicationType |
Journal Article
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