Linked Life Data

8932535

Source:http://linkedlifedata.com/resource/pubmed/id/8932535

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-4-3
pubmed:abstractText
We have recently reported that the flux of L-arginine through arginase in enterocytes is increased in weaned pigs when compared with suckling animals (Blachier et al. 1993, Eur. J. Biochem. 216, 109-117). The aim of the present study was to characterize arginase activities at both stages of development. Enterocytes isolated from suckling animals were found to possess an anionic (50%) and a non-anionic (50%) form of arginase as judged from activities recovered from DEAE-cellulose ion exchange chromatography. In enterocytes isolated from weaned animals, anionic arginase was the major form representing 89% of arginase activity. This isoform is characterized by increased affinity for L-arginine (2 fold) and increased maximal velocity (39 fold) when compared with the anionic form originating from suckling piglet enterocytes. In conclusion, our data demonstrate that pig enterocytes are equipped with at least 2 isoforms of arginase and that anionic form of arginase activity appeared to be mainly responsible for the capacity of weaned pig enterocytes to catabolize L-arginine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1039-9712
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-204
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Evidence for increased anionic arginase activity in pig enterocytes during development.
pubmed:affiliation
Unite d'Ecologie et de Physiologie du Systeme Digestif, Institut National de la Recherche Agronomique, Jouy-en-Josas, France.
pubmed:publicationType
Journal Article