Linked Life Data

8932500

Source:http://linkedlifedata.com/resource/pubmed/id/8932500

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-3-28
pubmed:abstractText
Obesity in males is accompanied by a significant decrease in testosterone levels. This decrease is essentially a consequence of the decrease of the sex hormone binding hormone (SHBG) binding capacity, itself probably the consequence of the increased insulin levels. In moderate obesity, free testosterone levels are normal, however, and there does not exist a real hypogonadism. In massively obese males, on the other hand, there is real hypogonadotrophic hypogonadism, with decreased free testosterone levels. The latter are the consequence of functional alterations at the hypothalamopituitary pole of the testicular axis, characterized by a decreased amplitude of the LH pulses. The decrease in adrenal androgen (DHEAS) levels is moderate and although it has been claimed that the increased insulin levels may play a causal role, the exact mechanism of this decrease is still a matter of controversy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0785-3890
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Decreased androgen levels and obesity in men.
pubmed:affiliation
Department of Endocrinology and Metabolism, University Hospital, Belgium.
pubmed:publicationType
Journal Article, Review