| pubmed-article:8925904 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C1367578 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0600139 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0002844 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C1518174 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0041904 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0332197 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0162493 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C2677316 | lld:lifeskim |
| pubmed-article:8925904 | lifeskim:mentions | umls-concept:C1508748 | lld:lifeskim |
| pubmed-article:8925904 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8925904 | pubmed:dateCreated | 1996-11-14 | lld:pubmed |
| pubmed-article:8925904 | pubmed:abstractText | A theoretical pathway of transcriptional regulation of the androgen receptor (AR) gene is via a cAMP response element (CRE) present in its promoter region (-508 to -501). After 20 h of stimulation with 8-bromo-cAMP, AR mRNA was upregulated in LNCaP but not in either PC-3 or DU-145 cell lines. We have demonstrated that the level of CRE binding protein (CREB) was the same in all cell lines and that the putative AR-CRE forms specific and compatible protein interactions with CREB. The ability to regulate AR gene transcription via the second messenger pathway is lost in the PC-3 and DU-145 cell lines. This may be an important primary mechanism of androgen insensitivity in prostate cancer. | lld:pubmed |
| pubmed-article:8925904 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8925904 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8925904 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8925904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8925904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8925904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8925904 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8925904 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8925904 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:8925904 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:8925904 | pubmed:author | pubmed-author:AbelPP | lld:pubmed |
| pubmed-article:8925904 | pubmed:author | pubmed-author:WaxmanJJ | lld:pubmed |
| pubmed-article:8925904 | pubmed:author | pubmed-author:LalaniE NEN | lld:pubmed |
| pubmed-article:8925904 | pubmed:author | pubmed-author:StampG WGW | lld:pubmed |
| pubmed-article:8925904 | pubmed:author | pubmed-author:StubbsA PAP | lld:pubmed |
| pubmed-article:8925904 | pubmed:author | pubmed-author:HurstHH | lld:pubmed |
| pubmed-article:8925904 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8925904 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:8925904 | pubmed:volume | 383 | lld:pubmed |
| pubmed-article:8925904 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8925904 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8925904 | pubmed:pagination | 237-40 | lld:pubmed |
| pubmed-article:8925904 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8925904 | pubmed:meshHeading | pubmed-meshheading:8925904-... | lld:pubmed |
| pubmed-article:8925904 | pubmed:meshHeading | pubmed-meshheading:8925904-... | lld:pubmed |
| pubmed-article:8925904 | pubmed:meshHeading | pubmed-meshheading:8925904-... | lld:pubmed |
| pubmed-article:8925904 | pubmed:meshHeading | pubmed-meshheading:8925904-... | lld:pubmed |
| pubmed-article:8925904 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8925904 | pubmed:articleTitle | Second messenger up-regulation of androgen receptor gene transcription is absent in androgen insensitive human prostatic carcinoma cell lines, PC-3 and DU-145. | lld:pubmed |
| pubmed-article:8925904 | pubmed:affiliation | Department of Histopathology, Royal Postgraduate Medical School Hammersmith Hospital, London, UK. | lld:pubmed |
| pubmed-article:8925904 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8925904 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8925904 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8925904 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8925904 | lld:pubmed |
