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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
13
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pubmed:dateCreated |
1996-11-8
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pubmed:abstractText |
In 1994 the authors published first results of anti-HCV antibodies in the group of 92 porphyria cutanea tarda patients, tested with ELISA second generation enzymatic method. Positivity, found in 21.7 per cent of them, was significantly higher when compared with the results of healthy blood-donors. Anti-HCV reactivity thus ascertained can be, however, non-specific in some cases and need not necessarily indicate existence of an active replication of hepatitis C-virus. The authors have therefore subsequently tried to verify the above results by the more sensitive polymerase chain reaction (PCR), enabling the proof of viral RNA and thus an assessment of the replication-activity of HCV. This study completes their previous findings for the evidence of viraemia in anti-HCV reactive PCT-patients.
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pubmed:language |
cze
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-7335
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
135
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
427-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8925541-Adult,
pubmed-meshheading:8925541-Aged,
pubmed-meshheading:8925541-Aged, 80 and over,
pubmed-meshheading:8925541-Chronic Disease,
pubmed-meshheading:8925541-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8925541-Female,
pubmed-meshheading:8925541-Hepacivirus,
pubmed-meshheading:8925541-Hepatitis C,
pubmed-meshheading:8925541-Hepatitis C Antibodies,
pubmed-meshheading:8925541-Humans,
pubmed-meshheading:8925541-Male,
pubmed-meshheading:8925541-Middle Aged,
pubmed-meshheading:8925541-Polymerase Chain Reaction,
pubmed-meshheading:8925541-Porphyrias, Hepatic,
pubmed-meshheading:8925541-RNA, Viral,
pubmed-meshheading:8925541-Viremia
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pubmed:year |
1996
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pubmed:articleTitle |
[Detection of HCV RNA in anti-HCV positive patients with chronic hepatic porphyria].
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pubmed:affiliation |
Dermatovenerologická klinika, LF UK, Praha.
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pubmed:publicationType |
Journal Article,
English Abstract
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