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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1997-2-18
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pubmed:abstractText |
We examined the possibility that human albumin solder can be used as a vehicle for site specific delivery of growth factors for the purpose of accelerating tissue repair following laser welded wound closure. Certain human recombinant growth factors have been shown to accelerate wound healing in model systems. Pilot in vitro studies have established that several growth factors, including TGF-beta 1, maintain bioactivity following exposure to temperatures achieved during laser tissue welding. Using a temperature controlled laser delivery system (TCL) to precisely maintain welding temperatures, it is now possible to avoid thermal denaturation of exogenous bioactive molecules such as growth factors.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0196-8092
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
360-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8923433-Albumins,
pubmed-meshheading:8923433-Animals,
pubmed-meshheading:8923433-Collagen,
pubmed-meshheading:8923433-Humans,
pubmed-meshheading:8923433-Laser Therapy,
pubmed-meshheading:8923433-Postoperative Period,
pubmed-meshheading:8923433-Skin,
pubmed-meshheading:8923433-Skin Physiological Phenomena,
pubmed-meshheading:8923433-Sutures,
pubmed-meshheading:8923433-Swine,
pubmed-meshheading:8923433-Tensile Strength,
pubmed-meshheading:8923433-Transforming Growth Factor beta,
pubmed-meshheading:8923433-Wound Healing
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pubmed:year |
1996
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pubmed:articleTitle |
Human albumin solder supplemented with TGF-beta 1 accelerates healing following laser welded wound closure.
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pubmed:affiliation |
Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|