Linked Life Data

8919360

Source:http://linkedlifedata.com/resource/pubmed/id/8919360

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-3-27
pubmed:abstractText
Using segregation and population analysis of serological data prepared in our laboratory, we have tentatively defined five OLA antigenic specificities: CO1.1, CO1.2, CO2.1 and CO2.2, whose genetic control would fit a model of two class I OLA loci (CO1.1 and CO1.2 first locus, CO2.1 and CO2.2 second locus, and CO3.1, that could represent a subtype of CO2.2. Alloantisera were obtained from Spanish Merino sheep by intrafamilial cross-immunization and from serum of primiparous and multiparous ewes. Screening of alloantisera for antilymphocyte reactivity was carried out by a two-step dye exclusion microcytotoxicity test against 216 animals belonging to different local breeds: Spanish Merino, Merino Landschaft, Manchega and Churra. Lymphocyte antigen specificities were characterized by cluster and correlation analysis, as well as family studies. Comparison of CO alloantisera with reference reagents from Scotland (CA reagents) showed an excellent correlation between CO1.1 and CA2, and CO2.1 and CA5. The reagents described can be used in various breeds, a characteristic important for their future applications.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0254-9670
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
268-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Serologically defined lymphocyte alloantigens in Spanish sheep.
pubmed:affiliation
Departmento de Genetica, Facultad de Veterinaria, Universidad de Cordoba, Espana.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't