Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1996-12-6
|
| pubmed:abstractText |
Several studies have shown that human immunodeficiency virus type 1 (HIV-1) is associated with an increase in the incidence of Kaposi's sarcoma and non-Hodgkin's lymphoma among homosexual men. The role of HIV-1 in increasing the incidence of other malignancies is more controversial. The incidence of non-Kaposi's sarcoma cancer was examined from 1978 to 1990 among 15,565 homosexual men who participated in studies of hepatitis B virus infection in the late 1970s in New York City, New York, and San Francisco, California. The standardized incidence ratio (SIR) for all cancers was 1.6 (95% confidence interval (CI) 1.4-1.8). Excesses were observed for non-Hodgkin's lymphoma (SIR = 12.7; 95% CI 11.0-14.6). Hodgkin's disease (SIR = 2.5; 95% CI 1.5-3.9), and anal cancer (SIR = 24.2 95% CI 13.5-39.9). As seen with non-Hodgkin's lymphoma, a cancer known to be associated with HIV-1. Hodgkin's disease incidence was significantly higher in more recent years compared with earlier years. No cases of Hodgkin's disease were found among HIV-1 antibody-negative men, and Hodgkin's disease was diagnosed near the time of initial acquired immunodeficiency syndrome diagnoses. Anal cancer incidence did not correlate with HIV-1 antibody status and did not tend to occur near the time of AIDS diagnoses. This study confirms the association of non-Hodgkin's lymphoma with HIV-1 infect on and suggests an association between Hodgkin's disease and HIV-1 infection. An excess in anal cancer was observed but did not appear to be associated with HIV-1 infection.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0002-9262
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
144
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
916-23
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8916502-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:8916502-Adult,
pubmed-meshheading:8916502-Anus Neoplasms,
pubmed-meshheading:8916502-HIV-1,
pubmed-meshheading:8916502-Hodgkin Disease,
pubmed-meshheading:8916502-Homosexuality, Male,
pubmed-meshheading:8916502-Humans,
pubmed-meshheading:8916502-Incidence,
pubmed-meshheading:8916502-Lymphoma, Non-Hodgkin,
pubmed-meshheading:8916502-Male,
pubmed-meshheading:8916502-Neoplasms,
pubmed-meshheading:8916502-New York City,
pubmed-meshheading:8916502-Risk Factors,
pubmed-meshheading:8916502-San Francisco
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Increased incidence of cancer among homosexual men, New York City and San Francisco, 1978-1990.
|
| pubmed:affiliation |
Wolf Szmuness Laboratory of Epidemiology, New York Blood Center, New York, USA.
|
| pubmed:publicationType |
Journal Article
|