Linked Life Data

8916379

Source:http://linkedlifedata.com/resource/pubmed/id/8916379

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-2-14
pubmed:abstractText
Sixteen normal human fetuses were studied at both 20-23 and 30-33 weeks of gestation to investigate whether hemodynamic changes in the heart and major fetal arteries occurred in response to maternal hyperoxygenation in normal pregnancy. Velocity waveforms from the mitral valve, aortic valve, middle cerebral artery, aortic isthmus and umbilical artery were recorded before and during maternal breathing of 100% oxygen. The cerebral artery pulsatility index (PI) increased with oxygen administration at the first examination (1.56 +/- 0.25, mean +/- 1 SD, to 1.72 +/- 0.28, p < 0.05). At the second examination this increase in cerebral artery PI was more consistent (1.89 +/- 0.43 to 2.22 +/- 0.43, p < 0.001) and there was also a decrease in the aortic isthmus PI (2.64 +/- 0.43 to 2.40 +/- 0.33, p < 0.01) during oxygen administration. The variables determined from the velocity waveforms of the umbilical artery, aortic and mitral valve did not show any changes with maternal hyperoxygenation. Maternal hyperoxygenation resulted in velocity waveform changes suggesting an increase of cerebral vascular resistance and a redistribution of blood flow from the brain to the vascular beds supplied by the descending aorta in the normal human fetus in the third trimester, but this response was less obvious at mid-gestation. The middle cerebral artery and the aortic isthmus seem to be suitable sites for verification of this response.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0960-7692
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
256-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Doppler echocardiographic assessment of fetal blood flow redistribution during maternal hyperoxygenation.
pubmed:affiliation
Department of Obstetrics and Gynecology, Danderyds Hospital, Stockholm, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't