Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1997-2-21
|
pubmed:abstractText |
Hepatitis E virus (HEV) is a major cause of non-A, non-B hepatitis in developing countries. Factors influencing sporadic spread of hepatitis E are unclear. We examined anti-HEV seroprevalence and demographic data from 407 urban and 360 rural black South African adults living in formal housing, squatter camps, or mud huts. Anti-HEV sero-prevalence ranged from 5.8% to 19.1% (mean 10.7%) in the different regions. Mean urban and rural rates were 6.6% and 15.3%, respectively (P = 0.0001). Rural mud hut dwellers, using unchlorinated river water, were at greater risk (17.4%) than rural villagers (5.3%; P = 0.008). A linear relation was found between seroprevalence and age, suggesting sporadic spread. The high prevalence in mud hut dwellers suggests that contaminated water plays a major role in HEV spread in South Africa. Routine chlorination or boiling of river drinking water before consumption may reduce HEV infection.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0146-6615
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
117-9
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8915876-Adult,
pubmed-meshheading:8915876-Cohort Studies,
pubmed-meshheading:8915876-Hepatitis Antibodies,
pubmed-meshheading:8915876-Hepatitis E,
pubmed-meshheading:8915876-Hepatitis E virus,
pubmed-meshheading:8915876-Humans,
pubmed-meshheading:8915876-Rural Population,
pubmed-meshheading:8915876-South Africa
|
pubmed:year |
1996
|
pubmed:articleTitle |
Hepatitis E in South Africa: evidence for sporadic spread and increased seroprevalence in rural areas.
|
pubmed:affiliation |
Department of Medicine, University of Cape Town, South Africa.
|
pubmed:publicationType |
Journal Article
|