Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1979-10-26
pubmed:abstractText
Since gonadal yolk-sac tumour in pure form or as a component of mixed germ cell tumour is in the majority of patients highly malignant, its histological recognition is of great prognostic importance. Yolk-sac tumour may assume various different histological guises, which have hitherto caused considerable terminological confusion; the present paper is aimed at correlating these morphological diversities with biochemical features which are consistent with yolk-sac differentiation. Using an enzyme-bridge immunoperoxidase technique, a series of 16 gonadal germ cell tumours with a yolk-sac component were screened for the presence of alpha-fetoprotein, alpha-1-antitrypsin, and transferrin. These proteins, normally produced by human yolk sac, were demonstrable in all the morphological patterns of yolk-sac tumour we have previously described. Six malignant non-germ cell tumours were submitted to the same investigations, and no evidence of the three protein markers was found in five; one tumour, however, an oat cell carcinoma of the bronchus, stained positively for transferrin.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-1203848, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-1203868, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-185553, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-321475, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-346612, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4106199, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4108552, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4126167, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4138965, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4170567, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4176107, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4182837, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4201655, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-47695, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-48375, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-4856386, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-49425, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-52995, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-5422910, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-5461338, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-5529798, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-557502, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-57717, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-59626, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-6067376, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-63318, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-63470, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-64253, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-72596, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-73740, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-75054, http://linkedlifedata.com/resource/pubmed/commentcorrection/89123-80417
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-9746
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
455-61
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Alpha-fetoprotein, alpha-1-antitrypsin, and transferrin in gonadal yolk-sac tumours.
pubmed:publicationType
Journal Article