rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
1997-3-18
|
pubmed:abstractText |
Initial warm cardioplegic reperfusion is widely used to ameliorate cardiac reperfusion damage after cardioplegic arrest. However, undesired effects of the high potassium concentration of the cardioplegic perfusate may limit the beneficial effect of this treatment. Contraction uncoupling by a negative inotropic and vasodilating agent such as 2,3-butanedione monoxime (BDM) may be superior to warm cardioplegic reperfusion in reducing reperfusion damage. Thus, initial reperfusion with BDM was compared with hyperkalemic reperfusion (HKR) after global ischemia of Langendorff-perfused guinea pig hearts.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1010-7940
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
897-904
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:8911845-Animals,
pubmed-meshheading:8911845-Cardioplegic Solutions,
pubmed-meshheading:8911845-Coronary Circulation,
pubmed-meshheading:8911845-Diacetyl,
pubmed-meshheading:8911845-Electrocardiography,
pubmed-meshheading:8911845-Guinea Pigs,
pubmed-meshheading:8911845-Heart Rate,
pubmed-meshheading:8911845-Isotonic Solutions,
pubmed-meshheading:8911845-Myocardial Contraction,
pubmed-meshheading:8911845-Myocardial Reperfusion,
pubmed-meshheading:8911845-Myocardial Reperfusion Injury,
pubmed-meshheading:8911845-Potassium,
pubmed-meshheading:8911845-Ventricular Function, Left
|
pubmed:year |
1996
|
pubmed:articleTitle |
Initial reperfusion with 2,3 butanedione monoxime is better than hyperkalemic reperfusion after cardioplegic arrest in isolated guinea pig hearts.
|
pubmed:affiliation |
Department of Anesthesiology, Medical College of Wisconsin, Milwaukee 53226, USA.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|