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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1996-12-13
|
| pubmed:abstractText |
Oesophagogastrectomy is the best available treatment for patients with carcinoma of the oesophagus or cardia. A retrospective analysis of our experience with 485 patients who were treated surgically forms the basis of this report. Of the 317 patients who underwent resection (resectability rate of 65%) only 210 were considered to be potentially curative. Overall, the 5-year survival rate for oesophageal cancer was 3%, whilst curative resection had a 5-year survival rate of 22% and varied according to stages. Five-year survival rate was 67.7% for patients with Stage I disease compared with 27.6, 9.4 and 6.4% for Stages IIa, IIb and III disease respectively. There were no 5-year survivors with Stage IV disease or with those patients who underwent an incomplete resection. Curative resection carried a mortality rate of 3.8%, whereas incomplete resection or palliative procedure carried higher mortality rates of 14 and 20.7% respectively. Adequate post-operative analgesia was provided by continuous extrapleural intercostal nerve block. Morbidity, mainly caused by respiratory complications, occurred in 30 patients (6.2%), with three patients requiring ventilatory support. Outcome was influenced mostly by the extent of the disease and the completeness of surgical resection rather than by histological type. We conclude that surgical treatment provides better longevity than any other type of therapy and remains the standard against which combined modality treatment should be compared. Our experience suggests that surgical treatment can be achieved with minimal morbidity and mortality.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0035-8835
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
41
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
295-301
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8908951-Aged,
pubmed-meshheading:8908951-Esophageal Neoplasms,
pubmed-meshheading:8908951-Esophagectomy,
pubmed-meshheading:8908951-Female,
pubmed-meshheading:8908951-Follow-Up Studies,
pubmed-meshheading:8908951-Gastrectomy,
pubmed-meshheading:8908951-Humans,
pubmed-meshheading:8908951-Male,
pubmed-meshheading:8908951-Neoplasm Staging,
pubmed-meshheading:8908951-Pain, Postoperative,
pubmed-meshheading:8908951-Prognosis,
pubmed-meshheading:8908951-Retrospective Studies,
pubmed-meshheading:8908951-Survival Rate,
pubmed-meshheading:8908951-Time Factors,
pubmed-meshheading:8908951-Treatment Outcome
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Results of surgical treatment of oesophageal cancer.
|
| pubmed:affiliation |
Department of Thoracic Surgery, Bradford Royal Infirmary, UK.
|
| pubmed:publicationType |
Journal Article
|