Linked Life Data

8908795

Source:http://linkedlifedata.com/resource/pubmed/id/8908795

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-12-19
pubmed:abstractText
The genetic composition of one tribal and two nontribal populations of the Chamba District, Himachal Pradesh, India, was studied by phenotype analyses of 25 genetic markers (9 blood groups, 13 red cell enzymes, and 3 serum proteins). Furthermore, the genetic structure of 11 populations from 3 districts, Chamba, Kangra, and Kinnaur of Himachal Pradesh, was also analyzed using data from 20 loci (57 alleles). Nine genetic systems (ABO, Rh, FY, P, PGM, ACP, AK, PGD, and HP) showed highly significant heterogeneity in the five populations of Kinnaur District, whereas among the six populations from Chamba and Kangra districts the genetic variation was low. The FIS value at each locus for the five populations of Kinnaur District and the six populations from Chambra and Kangra districts was consistently higher than the FST estimates, suggesting that the population structure of both regions is influenced by local random inbreeding. Although the role of selection in local genetic differentiation cannot be ruled out, the present analyses indicate that local differentiation is mainly affected by geographic proximity, random inbreeding, and admixture.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0018-7143
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
629-54
pubmed:dateRevised
2011-4-18
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Variability of genetic markers in Himachal Pradesh, India: variation among the subpopulations.
pubmed:affiliation
Department of Human Genetics, University of Newcastle upon Tyne, England.
pubmed:publicationType
Journal Article