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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1997-2-20
|
| pubmed:abstractText |
In type I allergy such as allergic rhinitis, not only immunocytes but also interleukin 4 (IL-4) and other cytokines are significant factors. In the present study we explored the course of change in IL-4 in the sera of allergic rhinitis patients upon immunotherapy. Assays of serum IL-4 were performed by the chemiluminescence sandwich enzyme immunoassay using AMPPD(3-(2'-spirodamantane)-4-methoxy-4-(3'-phophoryloxy+ ++) phenyl-1,2-dioxetane). The results indicated that immunotherapy reduced the IL-4 level from the pre-treatment baseline but not significantly. However, as far as good responses to the therapy are concerned a significant decrease in IL-4 was seen, and s-CD23, assayed at the same time, was also significantly decreased by immunotherapy.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0365-5237
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
525
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
98-104
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8908280-Antibodies, Monoclonal,
pubmed-meshheading:8908280-Humans,
pubmed-meshheading:8908280-Immunoglobulin E,
pubmed-meshheading:8908280-Immunotherapy,
pubmed-meshheading:8908280-Interleukin-4,
pubmed-meshheading:8908280-Luminescent Measurements,
pubmed-meshheading:8908280-Receptors, IgE,
pubmed-meshheading:8908280-Rhinitis, Allergic, Seasonal
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Study on changes in the level of serum IL-4 and soluble CD 23(s-CD23) with immunotherapy in nasal allergy patients.
|
| pubmed:affiliation |
Department of Otorhinolaryngology, Nagoya City University Medical School, Japan.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|