Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-4
pubmed:dateCreated
1997-3-12
pubmed:abstractText
Findings from the last two years in signal transduction research, including the elucidation of the crystal structure of alpha1, the uncovering of multiple roles for lipidation, the mimicry of receptor action with peptides, and both the in vitro reconstitution of inhibition of adenylyl cyclase and the in cell reconstitution of receptor-G protein coupling in transient and stable expression studies, are integrated into a "current" view of the receptor --> G protein --> effector pathway. The question is raised whether receptor or betagamma is the nucleotide exchange factor, and the central participation of Mg2+ in G protein activation and the change in affinity of the G protein for Mg2+ during receptor-stimulated activation are stressed.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1079-9893
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-52
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Signal transduction by G proteins: 1994 edition.
pubmed:affiliation
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review