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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-2-20
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pubmed:abstractText |
We mapped the locations of the genes encoding the slow skeletal muscle, fast skeletal muscle, and cardiac isoforms of troponin I (Tnni) in the mouse genome by interspecific hybrid backcross analysis of species-specific (C57BL/6 vs Mus spretus) restriction fragment length polymorphisms (RFLPs). The slow skeletal muscle troponin I locus (Tnni1) mapped to Chromosome (Chr) 1. The fast skeletal muscle troponin I locus (Tnni2), mapped to Chr 7, approximately 70 cM from the centromere. The cardiac troponin I locus (Tnni3) also mapped to Chr 7, approximately 5-10 cM from the centromere and unlinked to the fast skeletal muscle troponin I locus. Thus, the troponin I gene family is dispersed in the mouse genome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0938-8990
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
13-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8903721-Animals,
pubmed-meshheading:8903721-Chromosome Mapping,
pubmed-meshheading:8903721-Cloning, Molecular,
pubmed-meshheading:8903721-Crosses, Genetic,
pubmed-meshheading:8903721-DNA, Complementary,
pubmed-meshheading:8903721-Gene Expression Regulation,
pubmed-meshheading:8903721-Genetic Markers,
pubmed-meshheading:8903721-Genome,
pubmed-meshheading:8903721-Haplotypes,
pubmed-meshheading:8903721-Mice,
pubmed-meshheading:8903721-Mice, Inbred Strains,
pubmed-meshheading:8903721-Muscle, Skeletal,
pubmed-meshheading:8903721-Myocardium,
pubmed-meshheading:8903721-Nucleic Acid Hybridization,
pubmed-meshheading:8903721-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:8903721-Troponin I
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pubmed:year |
1996
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pubmed:articleTitle |
Cardiac and skeletal muscle troponin I isoforms are encoded by a dispersed gene family on mouse chromosomes 1 and 7.
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pubmed:affiliation |
Institut Pasteur de Paris, Unite de Genetique des mammiferes, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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