|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006462,
umls-concept:C0020962,
umls-concept:C0162757,
umls-concept:C0442805,
umls-concept:C0681850,
umls-concept:C0750480,
umls-concept:C1332714,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
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|
pubmed:issue |
12
|
|
pubmed:dateCreated |
1997-2-26
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|
pubmed:abstractText |
We have previously shown that drugs that decrease intracellular cAMP levels increase/restore the proliferative and cytotoxic capacity of T cells from HIV-seropositive subjects in vitro. Buspirone, a serotonin receptor agonist, indirectly decreases intracellular cAMP levels in T cells and has the same increasing/restoring effect on T-cell proliferation in lymphocytes from HIV-seropositive subjects in vitro.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0269-9370
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1339-47
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:8902062-Adult,
pubmed-meshheading:8902062-Biopterin,
pubmed-meshheading:8902062-Buspirone,
pubmed-meshheading:8902062-CD4 Lymphocyte Count,
pubmed-meshheading:8902062-CD4-CD8 Ratio,
pubmed-meshheading:8902062-Cell Division,
pubmed-meshheading:8902062-Cells, Cultured,
pubmed-meshheading:8902062-Female,
pubmed-meshheading:8902062-Flow Cytometry,
pubmed-meshheading:8902062-HIV Seropositivity,
pubmed-meshheading:8902062-Humans,
pubmed-meshheading:8902062-Lymphocytes,
pubmed-meshheading:8902062-Male,
pubmed-meshheading:8902062-Middle Aged,
pubmed-meshheading:8902062-Neopterin,
pubmed-meshheading:8902062-RNA, Viral,
pubmed-meshheading:8902062-Receptors, Interleukin-2,
pubmed-meshheading:8902062-beta 2-Microglobulin
|
|
pubmed:year |
1996
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|
pubmed:articleTitle |
Buspirone, a serotonin receptor agonist, increases CD4 T-cell counts and modulates the immune system in HIV-seropositive subjects.
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|
pubmed:affiliation |
Department of Clinical Immunology, Copenhagen University Hospitals, Hvidovre, Denmark.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
