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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1996-12-27
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pubmed:abstractText |
The fatty acid composition of heart, kidney, and lung was studied in weanling rats fed three diets differing in their polyunsaturated fatty acid content for 0, 2, and 4 wk. The first group had a 10% w/w fat semipurified diet which consisted of a mixture of olive oil (62.5%), soybean oil (11.1%), and refined coconut oil (26.4%) and provided 18:1n-9, 18:2n-6, and 18:3n-3 in similar amounts to a maternal human milk (diet HO). The second group received 7% of HO fat and 3% fish oil (0.4% 20:4n-6 and 5% 22:6n-3 of total fatty acids) (diet FO), and the third group was fed 7% HO fat, 1.5% of the same fish oil, and 1.5% of a purified pig brain phospholipid concentrate (0.6% 20:4n-6 and 3.5% 22:6n-3 of total fatty acids) (diet FO + BPL). The experimental diets increased tissue monounsaturated fatty acids in comparison with rats at weaning. Tissue lipid content of 20:4n-6 was increased and 22:6n-3 decreased in Group HO compared with weanling rats, whereas opposite changes were observed in Group FO. Feeding diet FO + BPL increased 22:6n:3 in tissue lipids compared with diet HO, and increased 20:4n-6 content in relation to diet FO. Our results indicate that rat heart, kidney, and lung are highly responsive to dietary n-3 and n-6 long-chain polyunsaturated fatty acids during postnatal life.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0024-4201
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
345-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8900466-Animals,
pubmed-meshheading:8900466-Fatty Acids,
pubmed-meshheading:8900466-Fatty Acids, Omega-3,
pubmed-meshheading:8900466-Fatty Acids, Omega-6,
pubmed-meshheading:8900466-Fatty Acids, Unsaturated,
pubmed-meshheading:8900466-Food, Formulated,
pubmed-meshheading:8900466-Kidney,
pubmed-meshheading:8900466-Lung,
pubmed-meshheading:8900466-Male,
pubmed-meshheading:8900466-Myocardium,
pubmed-meshheading:8900466-Rats,
pubmed-meshheading:8900466-Rats, Wistar,
pubmed-meshheading:8900466-Weaning
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pubmed:year |
1996
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pubmed:articleTitle |
Dietary long-chain polyunsaturated fatty acids modify heart, kidney, and lung fatty acid composition in weanling rats.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, University of Granada, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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