Linked Life Data

889961

Source:http://linkedlifedata.com/resource/pubmed/id/889961

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1977-10-14
pubmed:abstractText
Considerable change in phospholipid composition of microsomal and mitochondrial rat liver membranes under 3,4-benzpyrene-induced cancerogenesis is observed. The content of main phospholipid fractions (phosphatidylethanolamines and phosphatidylcholines) in rat liver microsomes increases at precancer stage and decreases during the tumour growth. On the contrary, the content of these phospholipids in mitochondrias decreases at precancer stage and increases at the period of vigerous tumour growth. The content of phosphatidylserines in rat liver microsomes sharply increases during the tumour growth, while in mitochondrias in decreases to an extremely low concentration beginning from early cancerogenesis stages. Lysophosphatides content in rat liver microsomes considerably increases under cancerogenesis. The noticeable amount of characteristic microsomal phospholipids, sphingomyelins, appears in rat liver mitochondrias under the growth of induced tumours. The peroxides of phosphatidylethanolamines and phosphatidylcholines appear in rat liver mitochondrias at later cancerogenesis stages, as compared with microsomes.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0320-9725
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
799-808
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
[Changes in phospholipid composition in rat liver microsomes and mitochondria under chemical carcinogenesis].
pubmed:publicationType
Journal Article, English Abstract