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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1996-12-11
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pubmed:abstractText |
Hemorrhagic transformation after cerebral ischemia is a well known clinical concern. The frequency of intact basal lamina (BL), identified by laminin antigen, in hemorrhagic and nonhemorrhagic zones after middle cerebral artery occlusion (MCA:O) and 3-h MCA:O with reperfusion in adolescent male baboons was assessed. Parenchymal hemoglobin was not detected prior to 24-h reperfusion. A significant decrease in the density of laminin (BL) in hemorrhagic zones (6.2 +/- 2.4) compared with nonhemorrhagic ischemic zones (10.5 +/- 2.4) (p < 0.05) and nonischemic basal ganglia (17.0 +/- 2.7) (p < 0.01) was observed. Time-dependent changes in BL integrity appear linked to the extravasation of blood components.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0271-678X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1373-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8898714-Animals,
pubmed-meshheading:8898714-Basement Membrane,
pubmed-meshheading:8898714-Brain Ischemia,
pubmed-meshheading:8898714-Cerebral Hemorrhage,
pubmed-meshheading:8898714-Laminin,
pubmed-meshheading:8898714-Male,
pubmed-meshheading:8898714-Microcirculation,
pubmed-meshheading:8898714-Papio,
pubmed-meshheading:8898714-Reperfusion Injury
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pubmed:year |
1996
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pubmed:articleTitle |
Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion.
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pubmed:affiliation |
Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, California 92037, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|