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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
|
| pubmed:dateCreated |
1997-2-5
|
| pubmed:abstractText |
This study characterizes the existence of a bronchial circulation in a marsupial, an animal which does not undergo placental development and does not have a ductus arteriosus. Direct perfusion of the lung by the pulmonary vasculature during the fetal development of opossums may occur, potentially eliminating the need for a bronchial circulation. We used radio- and fluorescent-labeled microspheres in conjunction with postmortem intravascular casting to determine if opossums have a systemic (bronchial) blood supply to the lung (n = 9). Gross postmortem examination of the intravascular casts showed a well-developed common bronchial artery. The histological distribution pattern of fluorescent microspheres was primarily to the airways. A few fluorescent microspheres were observed in the alveolar capillaries, indicating that a precapillary bronchial-to-pulmonary anastomosis exists in the opossum. Using the reference flow technique, total bronchial blood flow to the left lung averaged 0.95 +/- 0.58 SE ml/min. The presence of a bronchial circulation in the opossum suggests that it is more than a vestigial structure from embryonic development, potentially supporting its functional importance for carrying nutrients to the airway.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0034-5687
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
105
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
77-83
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:8897653-Animals,
pubmed-meshheading:8897653-Blood Circulation,
pubmed-meshheading:8897653-Blood Pressure,
pubmed-meshheading:8897653-Bronchial Arteries,
pubmed-meshheading:8897653-Fluorescent Dyes,
pubmed-meshheading:8897653-Lung,
pubmed-meshheading:8897653-Marsupialia,
pubmed-meshheading:8897653-Microscopy,
pubmed-meshheading:8897653-Microspheres,
pubmed-meshheading:8897653-Opossums,
pubmed-meshheading:8897653-Pulmonary Circulation
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Bronchial circulation in the marsupial opossum, Didelphis marsupialis.
|
| pubmed:affiliation |
Department of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Seattle, USA. susan@colossus.pulmcc.washington.edu
|
| pubmed:publicationType |
Journal Article
|