Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-12-4
pubmed:abstractText
There have been claims of an increased risk for gestational trophoblastic disease (i.e., hydatidiform mole and choriocarcinoma) in Vietnam since the period of Agent Orange sprayings. In 1990, we conducted a case-control study in Ho Chi Minh City to investigate risk factors for gestational trophoblastic disease in Vietnam. Eighty-seven married women, all of whom had a recent pathologic diagnosis of gestational trophoblastic disease, identified in the Obstetrical and Gynecological Hospital, were included in the study. Eighty-seven married women who were admitted mainly in the surgery departments of the same hospital were the controls, and they were matched to cases for age and area of residence. Odds ratios (ORs), adjusted for matching variables and other potential confounders, were estimated with unconditional logistic regression. A statistically significant trend in risk was observed with previous live births (p = .01). Cases were found to eat less meat per wk (OR = 0.4, 95% confidence interval [95% CI] = 0.2-0.9 for > or = five meat dishes) and to own fewer consumer goods than controls. An increase in risk was associated with the breeding of pigs (OR = 5.7, 95% CI = 1.2-27.6 for raising three or more pigs). A cumulative Agent Orange exposure index was constructed, using the patient's complete residence history. No significant difference was found between cases and controls for this index (OR = 0.7, 95% CI = 0.2-1.8 for high-exposure category), nor was such a difference noted for the agricultural use of pesticides.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-9896
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
368-74
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:8896386-2,4,5-Trichlorophenoxyacetic Acid, pubmed-meshheading:8896386-2,4-Dichlorophenoxyacetic Acid, pubmed-meshheading:8896386-Adult, pubmed-meshheading:8896386-Animal Husbandry, pubmed-meshheading:8896386-Animals, pubmed-meshheading:8896386-Case-Control Studies, pubmed-meshheading:8896386-Defoliants, Chemical, pubmed-meshheading:8896386-Female, pubmed-meshheading:8896386-Humans, pubmed-meshheading:8896386-Logistic Models, pubmed-meshheading:8896386-Maternal Exposure, pubmed-meshheading:8896386-Odds Ratio, pubmed-meshheading:8896386-Pregnancy, pubmed-meshheading:8896386-Questionnaires, pubmed-meshheading:8896386-Risk Factors, pubmed-meshheading:8896386-Swine, pubmed-meshheading:8896386-Tetrachlorodibenzodioxin, pubmed-meshheading:8896386-Trophoblastic Neoplasms, pubmed-meshheading:8896386-Uterine Neoplasms, pubmed-meshheading:8896386-Vietnam
pubmed:articleTitle
Agent orange and the risk of gestational trophoblastic disease in Vietnam.
pubmed:affiliation
Institut National de la Santé et de la Recherche Médicale, Villejuif, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't