Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1977-9-29
|
pubmed:abstractText |
This study was undertaken to evaluate relationships between blood or serum levels of lead (Pb), calcium, and 25-hydroxyvitamin D (25-OHD), within the framework of a nutritional survey of lead-burdened children. The results demonstrate that: regardless of blood Pb concentration and season of the year, serum 25-OHD concentration reflects vitamin D intake; high blood Pb (greater than or equal to 60 microgram/dl) was associated with decreased levels of 25-OHD (18+/--1 ng/ml vs. 32+/- in controls, P less than .001); concentrations Pb and calcium were inversely correlated in control and lead-burdened children; and children in the high blood Pb group (greater than or equal to 60 microgram/dl) had lower mean daily intakes of both calcium (610 +/- 20 mg vs. 770 +/- 20 in controls, P less than .001) and vitamin D (210 +/- 17 IU vs. 325 +/- 20 in controls, P less than .001). These data indicate that, in Pb-burdened children, multiple factors modify the absorption and toxicity of Pb, and relative vitamin D deficiency, not excess, is associated with high blood Pb levels. Assessment of nutrition, calcium metabolism, and vitamin D status is recommended in evaluating children known to have undue absorption of Pb.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkaline Phosphatase,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium, Dietary,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxycholecalciferols,
http://linkedlifedata.com/resource/pubmed/chemical/Lead,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphates,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin,
http://linkedlifedata.com/resource/pubmed/chemical/Vitamin D
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0003-9896
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
160-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:889354-Alkaline Phosphatase,
pubmed-meshheading:889354-Calcium,
pubmed-meshheading:889354-Calcium, Dietary,
pubmed-meshheading:889354-Child,
pubmed-meshheading:889354-Child, Preschool,
pubmed-meshheading:889354-Diet,
pubmed-meshheading:889354-Female,
pubmed-meshheading:889354-Humans,
pubmed-meshheading:889354-Hydroxycholecalciferols,
pubmed-meshheading:889354-Infant,
pubmed-meshheading:889354-Lead,
pubmed-meshheading:889354-Male,
pubmed-meshheading:889354-Nutrition Surveys,
pubmed-meshheading:889354-Phosphates,
pubmed-meshheading:889354-Serum Albumin,
pubmed-meshheading:889354-Vitamin D
|
pubmed:articleTitle |
Interactions of lead, calcium, vitamin D, and nutrition in lead-burdened children.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|