Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-1-28
pubmed:abstractText
The serological response to Bartonella henselae, B. quintana, and Afipia felis was assessed by an indirect fluorescence antibody test (IFAT) in 64 patients with suspected cat-scratch disease (CSD) recruited from the Bordeaux area in France. Blood samples were collected from 57 patients with chronic lymphadenopathy who underwent lymph-node biopsy with suggestive histopathologic features of CSD, and from an additional 7 patients with suspected CSD who underwent surgical incision and drainage because of lymph-node tenderness. Of the patients, 31 were male and 33 female, with a median age of 27 years (range 2-89). 69.8% reported cat and/or dog contact. Of the 26/64 (40.6%) patients, serum samples were positive at a titer of 1:100 or more for immunoglobulin G (IgG) antibodies (17 only to B. henselae, 1 only to B. quintana, 3 only to Afipia felis, and 5 to both B. henselae and B. quintana). IgM or IgA antibodies were also detected in 10 patients with IgG antibodies to B. henselae. 11 (17.2%) of the 64 patient serum samples were positive at a low titer of 1:50. These data suggested that serological response assessed by standard IFAT is not enough to confirm a CSD diagnosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0036-5548
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
361-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:8893399-Adolescent, pubmed-meshheading:8893399-Adult, pubmed-meshheading:8893399-Aged, pubmed-meshheading:8893399-Aged, 80 and over, pubmed-meshheading:8893399-Antibodies, Bacterial, pubmed-meshheading:8893399-Antigens, Bacterial, pubmed-meshheading:8893399-Bartonella henselae, pubmed-meshheading:8893399-Bartonella quintana, pubmed-meshheading:8893399-Cat-Scratch Disease, pubmed-meshheading:8893399-Child, pubmed-meshheading:8893399-Child, Preschool, pubmed-meshheading:8893399-Female, pubmed-meshheading:8893399-Fluorescent Antibody Technique, Indirect, pubmed-meshheading:8893399-Gram-Negative Bacteria, pubmed-meshheading:8893399-Humans, pubmed-meshheading:8893399-Immunoglobulin A, pubmed-meshheading:8893399-Immunoglobulin G, pubmed-meshheading:8893399-Immunoglobulin M, pubmed-meshheading:8893399-Infant, pubmed-meshheading:8893399-Lymphatic Diseases, pubmed-meshheading:8893399-Male, pubmed-meshheading:8893399-Middle Aged, pubmed-meshheading:8893399-Serologic Tests
pubmed:year
1996
pubmed:articleTitle
Evaluation of serological response to Bartonella henselae, Bartonella quintana and Afipia felis antigens in 64 patients with suspected cat-scratch disease.
pubmed:affiliation
Service de Maladies Infectieuses et Médecine Interne, Hôpital Pellegrin, France.
pubmed:publicationType
Journal Article