Linked Life Data

8889873

Source:http://linkedlifedata.com/resource/pubmed/id/8889873

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-2-10
pubmed:abstractText
This study was performed to determine the effects of essential fatty acid-deficient diet (EFAD) on immune parameters at 24 hours and 1 week after burn injury. Sprague Dawley rats were fed an EFAD diet or chow diet for 14 days. Twenty percent of the animals were put to death before the burn treatment (day 0), and the remainder were selected randomly to receive a scald or sham injury. Elevation in natural killer cell activity for EFAD-fed animals compared with rats fed the control diet was demonstrated at 100:1 effector:target (E:T) ratio on postburn day 1, and 25:1 E:T ratio on postburn day 7. EFAD-fed animals had significantly higher T-cell proliferation for all doses of phytohemagglutinin than did control animals before the burn injury. One week after the injury, EFAD-fed animals' T-cell activity was reduced to a level equivalent to that of control chow animals, whereas burned chow rats' lymphocyte activity was diminished significantly. EFAD diets enhanced T-cell proliferation and modestly improved natural killer cell response in both burned and control animals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0273-8481
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
465-70; discussion 464
pubmed:dateRevised
2006-8-15
pubmed:meshHeading
pubmed:articleTitle
Modulation of immune response in thermal injury by essential fatty acid-deficient diet.
pubmed:affiliation
Departments of Surgery, Texas Tech University Health Sciences Center, Lubbock 79417, USA.
pubmed:publicationType
Journal Article