Linked Life Data

8889463

Source:http://linkedlifedata.com/resource/pubmed/id/8889463

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1997-1-14
pubmed:abstractText
We describe the first case of Budd-Chiari syndrome due to homozygosity for factor V Leiden resulting in resistance to activated protein C. This is now recognized as the most common procoagulant disorder, and may account for many cases of Budd-Chiari syndrome previously though to be idiopathic or due to a latent myeloproliferative disorder. A further unique feature of this case is that the patient required orthotopic liver transplantation following failure of portacaval shunting and progressive hepatic necrosis. We demonstrated that liver transplantation resulted in correction of the serum coagulation abnormality; however, it is unlikely to have cured the disorder as platelet factor V would still be of the Leiden phenotype.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0954-691X
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
925-7
pubmed:dateRevised
2009-10-16
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Acute Budd-Chiari syndrome treated by liver transplantation in a woman homozygous for factor V Leiden.
pubmed:affiliation
Liver Transplantation Unit, Royal Free Hospital, London, UK.
pubmed:publicationType
Journal Article, Case Reports