Linked Life Data

8889005

Source:http://linkedlifedata.com/resource/pubmed/id/8889005

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-1-23
pubmed:abstractText
Ovariectomized rats with cannula over the medial basal hypothalamus (MBH) received implants of 3 alpha-diol conjugated to bovine serum albumin (BSA; 3 alpha-diol:BSA), free 3 alpha-diol diluted with BSA (3 alpha-diol&BSA), progesterone (P) conjugated to BSA (P:BSA), free P diluted with BSA (P&BSA), or BSA alone. 3 alpha-diol:BSA or 3 alpha-diol&BSA facilitated receptivity within 90 min. Other estradiol-treated rats received steroid implants in the preoptic area (POA); those receiving P:BSA or P&BSA showed significant elevations in lordosis in 5 min. When systemic P was given, 3 alpha-diol:BSA and 3 alpha-diol&BSA applied to the MBH or POA inhibited receptivity. When 3 alpha-diol was given systemically, 3 alpha-diol:BSA implants to the MBH and POA produced facilitatory effects. These data suggest 3 alpha-diol can act at the membrane and that these effects are influenced by circulating steroids; yet membrane-mediated actions do not account for all of P-facilitated sexual behavior in the MBH and POA.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0735-7044
pubmed:author
pubmed:issnType
Print
pubmed:volume
110
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
603-12
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Progesterone and 3 alpha-androstanediol conjugated to bovine serum albumin affects estrous behavior when applied to the MBH and POA.
pubmed:affiliation
Department of Biology, Boston University, USA. cafry@conncoll.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't