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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1997-2-3
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pubmed:abstractText |
Platelet hyperfunction is a typical feature of the prothrombotic state that frequently complicates the natural history of diabetes. In uremia, a bleeding diathesis is present, which principally involves the primary phase of hemostasis. Thus, in patients with uremia of diabetic origin, the infrequent coexistence of two opposite alterations of hemostasis takes place. In patients with uremia, an increased incidence of cardiovascular events and related mortality is observed. This phenomenon is greatly amplified in uremia of diabetic origin. Calcium homeostasis is a critical aspect of platelet function, which has recently become available in human diseases. The aim of this study was to evaluate calcium homeostasis in platelets from patients with uremia of diabetic and nondiabetic origin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0149-5992
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1062-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8886550-Biological Markers,
pubmed-meshheading:8886550-Blood Platelets,
pubmed-meshheading:8886550-Calcium,
pubmed-meshheading:8886550-Cardiovascular Diseases,
pubmed-meshheading:8886550-Diabetic Nephropathies,
pubmed-meshheading:8886550-Female,
pubmed-meshheading:8886550-Hemostasis,
pubmed-meshheading:8886550-Homeostasis,
pubmed-meshheading:8886550-Humans,
pubmed-meshheading:8886550-Kidney Failure, Chronic,
pubmed-meshheading:8886550-Male,
pubmed-meshheading:8886550-Middle Aged,
pubmed-meshheading:8886550-Reference Values,
pubmed-meshheading:8886550-Thrombin,
pubmed-meshheading:8886550-Uremia
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pubmed:year |
1996
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pubmed:articleTitle |
Deranged platelet calcium homeostasis in diabetic patients with end-stage renal failure. A possible link to increased cardiovascular mortality?
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pubmed:affiliation |
Department of Medicine, IRCCS H. San Raffaele, Milano, Italy.
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pubmed:publicationType |
Journal Article,
In Vitro
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