Linked Life Data

8886084

Source:http://linkedlifedata.com/resource/pubmed/id/8886084

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-12-10
pubmed:abstractText
Unilateral medial meniscectomy was performed on two groups of sheep. At 1 week post-operatively, one group (N = 5) underwent a regimen of moderate walking exercise (24 km/week), while the other group (N = 5) received no exercise. Two groups (N = 6 and 8) of unoperated sheep were used as exercised and unexercised controls for the respective meniscectomized groups. Six months post-surgery all groups were sacrificed and their knee joints were examined macroscopically using established scoring systems. In both groups, meniscectomy induced cartilage and bone changes typical of early hypertrophic osteoarthritis. However, meniscectomized animals subjected to the exercise program developed more severe cartilage lesions and osteophytes than their unexercised counterparts. While the cell density in femoral cartilage of the meniscectomized and exercised group was similar to controls, that of the meniscectomized but unexercised animals was higher. We conclude form these data that in this animal model exercise exacerbated the lesions induced in articular cartilage by meniscectomy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1063-4584
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
89-96
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Moderate exercise exacerbates the osteoarthritic lesions produced in cartilage by meniscectomy: a morphological study.
pubmed:affiliation
Veterinary School, Murdoch University, Western Australia, Australia.
pubmed:publicationType
Journal Article