Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-1-30
pubmed:abstractText
Mechanically ventilated patients have a higher incidence of pneumonia and mortality than do nonventilated patients. Ventilator-associated pneumonia (VAP) is diagnosed clinically, by bronchoscopy or "blind" bronchoalveolar lavage (BAL) or protected specimen brush (PSB), and by quantitative endobronchial aspirates (QEA). VAP is usually caused by bacteria, but Legionella pneumophila, Mycobacterium tuberculosis, viruses, and fungi are also potential pathogens. Bacteria causing nosocomial pneumonia may be part of the patient's endogenous flora, originate from other patients, hospital personnel, or environmental sources. Pseudomonas aeruginosa, Acinetobacter spp, and Staphylococcus aureus are the most common causative agents in late-onset nosocomial pneumonia, and Streptococcus pneumoniae and Hemophilus influenzae are more commonly found in early-onset pneumonia. Aspiration appears to be the major route for the entry of bacteria into the lower respiratory tract. Host factors, oropharyngeal and gastric colonization, cross-infection, and complications from the use of antibiotics and nasogastric and endotracheal tubes increases the risk of bacterial VAP. A working knowledge of the epidemiology and strategies for prevention of VAP should reduce infection rates, morbidity, and mortality in critically ill patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0882-0546
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
32-53
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Nosocomial pneumonia in mechanically ventilated adult patients: epidemiology and prevention in 1996.
pubmed:affiliation
Department of Medicine, Boston University School of Medicine, Boston City Hospital Division of Infectious Diseases, Thorndike Memorial Laboratory, MA, USA.
pubmed:publicationType
Journal Article, Review