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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
|
pubmed:dateCreated |
1997-1-29
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pubmed:abstractText |
Extracellular single unit recordings were made from spinal dorsal horn wide dynamic range neurons in spinal transected, urethane-anesthetized rats. The unit discharges elicited by noxious electrical stimulation of the hind paw were suppressed by electroacupuncture (15 Hz, 0.3 ms, 3 mA, 30 min) placed at the hind leg points (S-36 and SP-6). Local spinal superfusion with naloxone (20 micrograms/15 microliters) or CCK-8 (10 ng/15 microliters) attenuated, whereas CCK-B receptor antagonist L365,260 (2.5 micrograms/15 microliters) enhanced the electroacupuncture effect. These findings provide further evidence for the notion that CCK-8, in the spinal cord, functions as an antiopioid substrate that antagonizes opioid- or electroacupuncture-induced analgesia.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0020-7454
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
241-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8884394-Animals,
pubmed-meshheading:8884394-Electroacupuncture,
pubmed-meshheading:8884394-Male,
pubmed-meshheading:8884394-Neurons,
pubmed-meshheading:8884394-Nociceptors,
pubmed-meshheading:8884394-Rats,
pubmed-meshheading:8884394-Rats, Wistar,
pubmed-meshheading:8884394-Sincalide,
pubmed-meshheading:8884394-Spinal Cord,
pubmed-meshheading:8884394-Time Factors
|
pubmed:year |
1996
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pubmed:articleTitle |
Cholecystokinin octapeptide reverses the inhibitory effect induced by electroacupuncture on C-fiber evoked discharges.
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pubmed:affiliation |
Neuroscience Research Center, Beijing Medical University, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|