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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1997-1-14
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pubmed:abstractText |
Sulfite is commonly used in pharmaceuticals as a preservative. We report a unique clinical presentation of localized periorbital edema on the left eye after administration of sulfite-containing dexamethasone. The patient's sulfite sensitivity was confirmed by sulfite oral provocation test: periorbital edema on the same site developed after ingestion of 200 mg sodium bisulfite. She was non-atopic and did not complain of any respiratory symptoms. Allergy skin prick test with 100 mg/ml sodium bisulfite showed a negative result. She also has aspirin-sensitive urticaria which was confirmed by oral provocation test. In conclusion, sulfite can induce a localized periorbital edema, an uncommon manifestation in sensitive patients. Further investigations are needed to clarify the pathogenetic mechanisms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
1011-8934
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
356-7
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pubmed:dateRevised |
2011-3-16
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pubmed:meshHeading |
pubmed-meshheading:8878807-Allergens,
pubmed-meshheading:8878807-Edema,
pubmed-meshheading:8878807-Female,
pubmed-meshheading:8878807-Humans,
pubmed-meshheading:8878807-Middle Aged,
pubmed-meshheading:8878807-Orbital Diseases,
pubmed-meshheading:8878807-Skin Diseases,
pubmed-meshheading:8878807-Sulfites
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pubmed:year |
1996
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pubmed:articleTitle |
Localized periorbital edema as a clinical manifestation of sulfite sensitivity.
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pubmed:affiliation |
Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
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pubmed:publicationType |
Journal Article,
Case Reports
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