rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1997-3-11
|
pubmed:abstractText |
In order to study the short-term effect of moderate and severe reduction of liver function by acetaminophen poisoning of different severity on gene expression for liver-specific functions, rats were given 3.75 and 7.5 g per kg body weight acetaminophen intragastrically. The lower dose is associated with low mortality; after the higher dose, most rats die at between 12 and 24 h.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0168-8278
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
183-90
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8878780-Acetaminophen,
pubmed-meshheading:8878780-Acute-Phase Proteins,
pubmed-meshheading:8878780-Animals,
pubmed-meshheading:8878780-Enzymes,
pubmed-meshheading:8878780-Female,
pubmed-meshheading:8878780-Liver,
pubmed-meshheading:8878780-Liver Regeneration,
pubmed-meshheading:8878780-Proteins,
pubmed-meshheading:8878780-RNA, Messenger,
pubmed-meshheading:8878780-Rats,
pubmed-meshheading:8878780-Rats, Wistar,
pubmed-meshheading:8878780-Urea
|
pubmed:year |
1996
|
pubmed:articleTitle |
Expression of liver-specific functions in rat hepatocytes following sublethal and lethal acetaminophen poisoning.
|
pubmed:affiliation |
Department of Medicine A, Rigshospitalet, Copenhagen, Denmark, tygstrup@rh.dk
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|