Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1997-2-7
|
pubmed:abstractText |
A 34-year-old man with acute myelocytic leukemia (AML: MO) and a 32-year-old woman with AML: M2 developed pure red cell aplasia (PRCA) after receiving a major ABO incompatible bone marrow transplant (BMT). The first patient responded to recombinant human erythropoietin (rhEPO) therapy, while the second did not. The second patient also received methylprednisolone (m-PSL) but developed reticulocytosis and hemolysis after the administration of m-PSL. Plasmapheresis was then performed and the patient promptly recovered from hemolysis and PRCA. We conclude that close attention must be paid when treating PRCA following major ABO-incompatible BMT with rhEPO and m-PSL, as there is always the potential for massive hemolysis.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0934-0874
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
506-8
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8875795-ABO Blood-Group System,
pubmed-meshheading:8875795-Acute Disease,
pubmed-meshheading:8875795-Adult,
pubmed-meshheading:8875795-Blood Group Incompatibility,
pubmed-meshheading:8875795-Bone Marrow Transplantation,
pubmed-meshheading:8875795-Erythropoietin,
pubmed-meshheading:8875795-Female,
pubmed-meshheading:8875795-Humans,
pubmed-meshheading:8875795-Leukemia, Myeloid,
pubmed-meshheading:8875795-Leukemia, Myeloid, Acute,
pubmed-meshheading:8875795-Male,
pubmed-meshheading:8875795-Models, Immunological,
pubmed-meshheading:8875795-Recombinant Proteins,
pubmed-meshheading:8875795-Red-Cell Aplasia, Pure,
pubmed-meshheading:8875795-Remission Induction,
pubmed-meshheading:8875795-Transplantation, Homologous
|
pubmed:year |
1996
|
pubmed:articleTitle |
Pure red cell aplasia after major ABO-incompatible bone marrow transplantation: two case reports of treatment with recombinant human erythropoietin.
|
pubmed:affiliation |
Department of Hematology and Chemotherapy, Kanagawa Cancer Center, Yokohama-city, Japan.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|