Linked Life Data

8875404

Source:http://linkedlifedata.com/resource/pubmed/id/8875404

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-4-17
pubmed:abstractText
A commercial phased-array multicoil was used to acquire water-suppressed localized proton spectra of the two major anatomical regions of the prostate. The signal-to-noise ratio and spectral resolution allowed identification of peaks from choline and creatine, as well as a major peak from citrate. Quantification of the citrate peak using experimentally determined relaxation parameters with tissue water as an internal concentration reference revealed a marked variability between different volunteers. Nevertheless, in each case, the citrate concentration was up to fourfold greater in the peripheral zone than in the central gland. Furthermore, the difference in citrate concentration between these two regions was positively correlated with the subjects age. The results indicate a consistent difference in cellular function between the major anatomical regions within the prostate and may have important consequences for the application of magnetic resonance spectroscopy to the diagnosis of prostatic pathology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0740-3194
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
352-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Quantification of citrate concentration in the prostate by proton magnetic resonance spectroscopy: zonal and age-related differences.
pubmed:affiliation
Centre for Magnetic Resonance Investigations, University of Hull, United Kingdom.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't