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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-11-20
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pubmed:abstractText |
The potent bisphosphonates offer great promise in the management of Paget's disease of bone, but are currently available only as parenteral preparations in most countries. There is a need for a well-tolerated, oral therapy. Furthermore, none of the currently available therapies have been rigorously demonstrated to heal the lytic bone lesions characteristic of this condition. Alendronate is a potent new oral aminobisphosphonate that has shown promising effects on Paget's disease in preliminary studies.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0002-9343
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pubmed:author |
pubmed-author:CundyTT,
pubmed-author:DufresneSS,
pubmed-author:HoskingD JDJ,
pubmed-author:KotowiczM AMA,
pubmed-author:LombardiAA,
pubmed-author:MurphyW AWAJr,
pubmed-author:MuslinerT ATA,
pubmed-author:NicholsonG CGC,
pubmed-author:ReidI RIR,
pubmed-author:ThompsonD EDE,
pubmed-author:WeinsteinR SRS,
pubmed-author:YatesA JAJ,
pubmed-author:YeapSS
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pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
341-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8873503-Administration, Oral,
pubmed-meshheading:8873503-Aged,
pubmed-meshheading:8873503-Aged, 80 and over,
pubmed-meshheading:8873503-Alendronate,
pubmed-meshheading:8873503-Alkaline Phosphatase,
pubmed-meshheading:8873503-Biopsy,
pubmed-meshheading:8873503-Bone and Bones,
pubmed-meshheading:8873503-Calcium,
pubmed-meshheading:8873503-Collagen,
pubmed-meshheading:8873503-Collagen Type I,
pubmed-meshheading:8873503-Double-Blind Method,
pubmed-meshheading:8873503-Female,
pubmed-meshheading:8873503-Humans,
pubmed-meshheading:8873503-Male,
pubmed-meshheading:8873503-Middle Aged,
pubmed-meshheading:8873503-Osteitis Deformans,
pubmed-meshheading:8873503-Peptides,
pubmed-meshheading:8873503-Phosphates
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pubmed:year |
1996
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pubmed:articleTitle |
Biochemical and radiologic improvement in Paget's disease of bone treated with alendronate: a randomized, placebo-controlled trial.
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pubmed:affiliation |
Department of Medicine, University of Auckland, New Zealand.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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