Linked Life Data

8872815

Source:http://linkedlifedata.com/resource/pubmed/id/8872815

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1997-1-9
pubmed:abstractText
A point mutation in the factor V gene (FV Q506) renders factor V resistant to inactivation by activated protein C. The frequency of this mutation is known to be significantly increased in patients with thrombophilia. There are conflicting reports on the significance of the polymorphism in patients with ischaemic heart disease. We determined the frequency of FV Q506 in a control Caucasian population, and compared it with 192 Caucasian patients admitted to coronary care and assessed as having myocardial infarction (MI) or unstable angina plus previous MI. There was no significant difference between the two groups. A cohort of 105 asymptomatic Afro-Caribbeans showed a much reduced frequency of the polymorphism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0950-9240
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
433-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Factor V Leiden polymorphism (FV Q506) in patients with ischaemic heart disease, and in different populations groups.
pubmed:affiliation
Medical Genetics Unit, St George's Hospital Medical School, London, UK.
pubmed:publicationType
Journal Article