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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1997-1-3
|
| pubmed:abstractText |
We report a case of haploidentical T-depleted BMT that engrafted durably after a highly immunosuppressive conditioning regimen. DNA polymorphism analysis showed that granulocytes and monocytes were donor type but T and B lymphocytes were host derived. Host tolerance to donor antigens was documented. The patient suffered from serious recurrent CMV infections until split chimaerism shifted to full donor type 2 years post-BMT. Seven years after BMT the patient remains in complete remission.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0268-3369
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
465-7
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8864466-Adult,
pubmed-meshheading:8864466-Bone Marrow Transplantation,
pubmed-meshheading:8864466-Chimera,
pubmed-meshheading:8864466-DNA,
pubmed-meshheading:8864466-Histocompatibility Testing,
pubmed-meshheading:8864466-Humans,
pubmed-meshheading:8864466-Leukemia, Myeloid, Acute,
pubmed-meshheading:8864466-Lymphocyte Depletion,
pubmed-meshheading:8864466-Male,
pubmed-meshheading:8864466-T-Lymphocytes
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Unusual split chimaerism after mismatched T-depleted BMT.
|
| pubmed:affiliation |
Haematology and Clinical Immunology, University of Perugia, Italy.
|
| pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|