Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1997-1-23
pubmed:abstractText
A total of 294 specimens collected from nonrespiratory sites of 268 patients were tested for direct detection of Mycobacterium tuberculosis complex by the Gen-Probe Amplified Mycobacterium tuberculosis Direct Test (AMTD). The specimens included ascitic, pleural, pericardial, and synovial fluids, abscess aspirates, and tissue and lymph node biopsy samples, as well as gastric aspirates and cerebrospinal fluid samples. All samples were processed by the N-acetyl-L-cysteine-sodium hydroxide decontamination procedure prior to testing. Twenty samples showed acid-fast bacilli on auramine staining, and 48 samples were positive by AMTD, 9 of which were negative for M. tuberculosis complex by culture. After reviewing the patients clinical charts to resolve discrepancies, the test result of one cerebrospinal fluid sample was considered to be false positive by AMTD. The overall sensitivity, specificity, positive predictive value, and negative predictive value were 83.9, 99.6, 97.9, and 96.3%, respectively. No significant differences were found when AMTD results obtained with specimens of nonrespiratory origin were compared with assay results obtained with samples of respiratory origin (P > 0.05). In conclusion, our results demonstrate that AMTD performs equally well with all types of specimens.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-13927224, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-1572974, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-1761694, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-7534230, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-7665654, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-7665659, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8027344, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8150948, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8308121, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8408564, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8567886, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8567906, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8567908, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8586682, http://linkedlifedata.com/resource/pubmed/commentcorrection/8862598-8681978
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2275-9
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Diagnosis of extrapulmonary tuberculosis by Gen-Probe amplified Mycobacterium tuberculosis direct test.
pubmed:affiliation
Institut für Medizinische Mikrobiologie und Infektionsinmunologie, Klinikum Benjamin Franklin, Freien Universität Berlin, Germany.
pubmed:publicationType
Journal Article