Linked Life Data

886223

Source:http://linkedlifedata.com/resource/pubmed/id/886223

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-9-22
pubmed:abstractText
An adaptation of the double-filter technique has been developed for the in vitro evaluation of monocyte leukotaxis. The assay, which employs a sandwich of a cell-permeable polycarbonate and a cell-impermeable cellulose nitrate filter membrane, is more reliable, reproducible, and sensitive than previous techniques without sacrificing their rapidity and simplicity. Leukotactic responses were directly proportional to monocyte concentrations varying from 1 X 10(5)/ml to 6 X 10(6)/ml. Kinetic studies indicated that there was a linear increase in leukotactic responses at incubation periods from 60 to 180 min. At incubation periods less than 60 min, leukotactic responses also increased linearly but at an accelerated rate. The leukotactic and chemokinetic effects of a leukoattractant may be discriminated and appear to exert antagonistic effects in this assay system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-2143
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
An improved method for the in vitro evaluation of monocyte leukotaxis.
pubmed:publicationType
Journal Article