Linked Life Data

8860356

Source:http://linkedlifedata.com/resource/pubmed/id/8860356

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1997-5-28
pubmed:abstractText
The array of diagnostic tools now available allows not only precise serological determination of past exposure to cytomegalovirus (CMV) infections but also identification of CMV components in blood during viraemia--predictive of CMV disease. Sensitive and rapid identification of CMV components from infected organs from biopsies and body fluids, such as cerebrospinal fluid and bronchoalveolar lavage fluid, is also possible. The polymerase chain reaction (PCR) has become a highly sensitive and specific diagnostic tool that now also can he applied in a quantitative or semiquantitative manner. Non-PCR methods, which amplify the signal rather than DNA itself, are also available as quantitative tests. The antigenaemia assay was the first quantitative measure of CMV load during viraemia. It is useful in the surveillance of CMV in transplant patients as well as for drug efficacy monitoring, and is the method of choice in many laboratories. The use of modern diagnostic tools and subsequent treatment with an appropriate antiviral drug should reduce the number of lethal CMV cases to a minimum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-8878
pubmed:author
pubmed:issnType
Print
pubmed:volume
100
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
64-71
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
The clinical relevance of different laboratory tests in CMV diagnosis.
pubmed:affiliation
Division of Clinical Virology, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden.
pubmed:publicationType
Journal Article, Review, Case Reports